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Blood: The Last Vampire is a 2000 Japanese animated action horror film directed by Hiroyuki Kitakubo, written by Kenji Kamiyama and produced by Production I.G. The film premiered in theaters in Japan on November 18, 2000. A single-volume manga sequel, titled Blood: The Last Vampire 2000 and written by Benkyo Tamaoki, was published in Japan in 2001 by Kadokawa Shoten, and in English by Viz Media in November 2002 under the title Blood: The Last Vampire 2002. Three Japanese light novel adaptations have also been released for the series, along with a video game. It also spawned a fifty-episode anime series set in an alternate universe titled Blood+ as well as a second anime series, Blood-C, also ....